Aplastic anemiaĪplastic anemia occurs when the body stops producing enough new blood cells. This may happen due to an autoimmune condition or other cause weakening the stomach lining, which makes cells that bind to vitamin B-12 so the intestines can digest them. Pernicious anemia is a rare disorder in which the body has trouble using vitamin B-12, a key component in making RBCs. More serious causes include blood loss from internal bleeding in the gastrointestinal tract or cancers. Iron deficiency anemiaĪ low dietary intake of iron or blood loss due to issues such as very heavy menstruation may cause iron deficiency anemia. There are different types of anemia, each with its own causes. This may happen due to changes in the cell itself or components of the cell, such as hemoglobin. Examples of RBC disorders that involve enzyme deficiencies include glucose-6-phosphate dehydrogenase deficiency and pyruvate kinase deficiency.Īnemia occurs when a person has a low number of healthy RBCs.
RBC enzymopathies are genetic conditions that affect the production of enzymes in RBCs and cell metabolism. Examples of cytoskeletal abnormalities include hereditary spherocytosis and elliptocytosis. Health experts may also refer to these conditions as RBC membranopathies. Examples of hemoglobinopathies include:Ĭytoskeletal abnormalities in RBCs include conditions that change the structure or permeability of the RBC or its membranes. Hemoglobinopathies cause an abnormal production or change the structure of the hemoglobin. Hemoglobin is an iron-rich molecule responsible for the red color of the cells. Hemoglobinopathies are disorders that involve the hemoglobin protein within RBCs. Some examples include: Hemoglobinopathies There are many types of RBC disorders, which health experts can categorize by the kind of structure they affect. RBC disorders are conditions that affect RBCs, which are responsible for carrying oxygen from the lungs to the rest of the body. Share on Pinterest Image Source/Getty Images
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